PI
Attila Tóth
e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Postdoc
Naga Sailaja Imjeti
I am a postdoc from India, and I have been member of the Toth lab since 2019. My main research question concerns how transcription and genome organization changes upon meiotic entry to enable meiotic recombination. To this end, I combine genome profiling (e.g. CUT&RUN-sequencing), transcriptomics (bulk and single cell RNAseq), biochemistry and genetics of a newly identified meiotic chromatin modulator that play crucial role in meiotic chromatin dynamics and recombination.
e-mail: naga_sailaja.imjeti(at)tu-dresden.de
Predocs
Sarai Valerio Cabrera
I am from Mexiko, and I started my lab life here in late 2017 as a PhD student.
One of the landmark processes of meiosis is the formation of chromosome axes, which are elongated proteinaceous structures at the cores of chromosomes. Chromosome axes are crucial for the correct recombination of parental genomes in meiocytes. Axes control DNA break formation, repair and the quality control of DNA break repair. Hence, the axis is essential for the generation of healthy euploid gametes and fertility. My aim has been to understand the molecular network that underpins the diverse roles of the axis.
e-mail: sarai.valerio_cabrera(at)tu-dresden.de
Kavya Raveendran
I am from India, and I joined the Toth lab in 2018. My goal has been to understand how the meiotic chromosome axis controls DNA break formation, DNA repair and the quality control of recombination. My project mainly focuses on the analysis of CRISPR/Cas9 edited mice where the functionality of key chromosome axis components, HORMAD1 and HORMAD2, is altered.
e-mail: Kavya.Raveendran(at)tu-dresden.de
Vlad Telychko
I am from Ukraina. I started my PhD in 2019 in the Toth lab. I am interested in the molecular mechanisms that enable correct meiotic recombination. I have combined biochemistry, ectopic protein interaction studies and the phenotypic analysis of mice where key meiotic proteins are mutated. My projects include functional studies of the chromosome axis, testing the role of a novel meiotic recombination protein and uncovering the mechanism that commit a subset of recombination intermediates to crossover formation.
Vladyslav.Telychko(at)tu-dresden.de
Master students
Swathi Srinivasan
I am from India. I joined the Toth lab in 2020. I am testing the role of a novel meiotic recombination protein that may have a function in homolog pairing. I have developed antibodies to my favorite protein and I am analysing the phenotype of mice where the protein was disrupted by CRISPR/Cas9.
swathi.srinivasan(at)mailbox.tu-dresden.de
Internship students
Matthias Weigel
(Germany)
privat(at)matthias-weigel.de
Anna Kapitonova
(Russia)
kapitonova.anna.2017(at)post.bio.msu.ru
Technicians
Mandy Munzig
mandy.munzig(at)tu-dresden.de